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A CIC bioGUNE study has found a new way to treat rare and aggressive liver cancer

The findings suggest that blocking the CNNM4 protein responsible for transporting magnesium inside cells could provide direct, safe and effective treatment, opening up new avenues for personalized therapies against this cancer.
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A team of CIC bioGUNE researchers have discovered a new way to treat rare and aggressive liver cancer. 

According to a note from the Basque Center for Biosciences ikerketa , the study concludes that theprotein  CNNM4, essential for the transport of magnesium, is produced excessively in colangiocarcinoma (CCA). 

According to the findings recently published in Gut magazine, blocking CNNM4 would make it possible to develop safe and effective treatment against this cancer.

The research has been led by Dr. Malu ○

The researchers, once this CNNM4 protein has been blocked, have succeeded in slowing tumor growth, reducing resistance to chemotherapy, and preventing the spread of tumor cells.

This liver cancer is often diagnosed late and is very resistant to treatment. Approximately 20-30% of patients are operated on to remove the tumor, but the survival rate is low. 

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